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5F-PB22
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$29.00 – $600.00

Molar mass: 376.431 g·mol−1

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SKU: N/A Category: Synthetic Cannabinoids Tags: 5F-PB22 For Sale, Buy 5F-PB22 Online, Order 5F-PB22 Online, Where to buy 5F-PB22 Online
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Description

5F-PB-22 (1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester also known as 5F-QUPIC is a synthetic cannabinoid and agonist of the cannabinoid receptors which produces predominantly sedating subjective effects somewhat similar to that of cannabis.

There is very little information regarding the pharmacology of this compound within the scientific literature. Despite this, however, it has been sold as a grey area research chemical through online vendors.

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5F-PB-22

Cannabinoids are commonly smoked or vaporized to achieve a quick onset of effects and rapid offset. 5F-PB-22 is orally active when dissolved in a lipid, which can increase the duration significantly. Like other cannabinoids, it is insoluble in water but dissolves in ethanol and lipids.

Unlike cannabis, the chronic abuse of synthetic cannabinoids has been associated with multiple deaths and more dangerous side effects and toxicity in general.

Five deaths have been associated with the use of 5F-PB-22 in the United States.

Therefore, it is strongly discouraged to take this substance for extended periods of time or in excessive doses.

5F-PB-22 (5F-QUPIC or quinolin-8-yl 1-pentyfluoro-1H-indole-3-8-carboxylate) is a designer drug which acts as a cannabinoid agonist. The structure of 5F-PB-22 appears to have been designed with an understanding of structure–activity relationships within the indole class of cannabinoids.

Synonyms
  • 5-fluoro QUPIC
Technical Information
Formal Name
1-(5-fluoropentyl)-1H-Indole-3-carboxylic acid, 8-quinolinyl ester
CAS Number
1400742-41-7
Molecular Formula
C23H21FN2O2
Formula Weight
376.4
Purity
≥98%
Formulation(Request formulation change)
A neat solid
Solubility
  • DMF: 16 mg/ml
  • DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml
  • DMSO: 11 mg/ml
SMILES
O=C(OC1=C(N=CC=C2)C2=CC=C1)C3=CN(CCCCCF)C4=C3C=CC=C4
InChi Code
InChI=1S/C23H21FN2O2/c24-13-4-1-5-15-26-16-19(18-10-2-3-11-20(18)26)23(27)28-21-12-6-8-17-9-7-14-25-22(17)21/h2-3,6-12,14,16H,1,4-5,13,15H2
InChi Key
MBOCMBFDYVSGLJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 3 years

Chemistry
5F-PB-22, or quinolin-8-yl 1-pentyfluoro-1H-indole-3-8-carboxylate, is a synthetic indolecarboxylate as it contains a substituted core indole structure.

This indole core is shared with other cannabinoid substances including PB-22, JWH-018, and AM2201. 5F-PB-22 is an ether with formula R-O-R’, which can be understood as a substance with two sub-units joined through an oxygen bridge.

The indole group of 5F-PB-22 is substituted at R5 with a fluoropentyl chain, a substitution shared with 5F-AKB48. Additionally, the indole core is substituted at R3 with a carboxylic acid group.

The terminal oxygen of this carboxylic acid is bonded through an ether bond to a quinoline group at location R8 of the heterocycle.

Additional information
Quantity

10 grams, 100 grams, 1gram, 25 grams, 2grams, 5 grams, 50 grams

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