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Amb-fubinaca
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SKU: N/A Category: Synthetic Cannabinoids Tags: Amb-fubinaca For Sale, Buy Amb-fubinaca Online, Order Amb-fubinaca Online, Where to buy Amb-fubinaca Online
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  • Description
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Description

MMB-FUBINACA  is an analytical reference material categorized as a synthetic cannabinoid. 1. MMB-FUBINACA is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

BUY AMB-FUBINACA.

AMB-FUBINACA.

AMB-FUBINACA (also known as FUB-AMB and MMB-FUBINACA) is an indazole-based synthetic cannabinoid that is a potent agonist for the cannabinoid receptors, with Ki values of 10.04 nM at CB1 and 0.786 nM at CB2 and EC50 values of 0.5433 nM at CB1 and 0.1278 nM at CB2,[1] and has been sold online as a designer drug.It was originally developed by Pfizer which described the compound in a patent in 2009, but was later abandoned and never tested on humans.

  • 5F-AB-PINACA
  • 5F-ADB
  • 5F-AMB
  • 5F-APINACA
  • AB-CHFUPYCA
  • AB-FUBINACA
  • AB-PINACA
  • ADB-CHMINACA
  • ADB-FUBINACA
  • ADB-PINACA
  • ADSB-FUB-187
  • APINACA
  • MDMB-CHMICA
  • MDMB-CHMINACA
  • MDMB-FUBINACA
  • PX-2
  • PX-3
Synonyms
Synonyms
  • ​AMB-FUBINACA
  • FUB-AMB
Technical Information
Formal Name
N-[[1-[(4-fluorophenyl)methyl]-1H-indazol-3-yl]carbonyl]-L-valine, methyl ester
CAS Number
1971007-92-7
Molecular Formula
C21H22FN3O3
Formula Weight
383.4
Purity
≥98%
Formulation(Request formulation change)
A neat solid
Solubility
  • DMF: 30 mg/ml
  • DMSO: 25 mg/ml
  • Ethanol: 30 mg/ml
  • Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
SMILES
FC(C=C1)=CC=C1CN2N=C(C(N[C@H](C(OC)=O)C(C)C)=O)C3=CC=CC=C32
InChi Code
InChI=1S/C21H22FN3O3/c1-13(2)18(21(27)28-3)23-20(26)19-16-6-4-5-7-17(16)25(24-19)12-14-8-10-15(22)11-9-14/h4-11,13,18H,12H2,1-3H3,(H,23,26)/t18-/m0/s1
InChi Key
FRFFLYJQPCIIQB-SFHVURJKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 7 years

Analysis of AMB-FUBINACA Biotransformation Pathways in Human Liver Microsome and Zebrafish Systems by Liquid Chromatography-High Resolution Mass Spectrometry

In this study, the metabolic profiles of a new illicit drug AMB-FUBINACA were investigated using both human liver microsome and zebrafish models.

Liquid chromatography Q Extractive HF Hybrid Quadrupole-Orbitrap mass spectrometry (LC-QE-HF-MS) was employed to analyze the metabolic sites and pathways. AMB-FUBINACA was added to the in vitro liver microsome incubation model to simulate the metabolic processes in human body.

The results showed that a total of 17 metabolites were generated in the human liver microsome model; the main metabolic pathways of the phase I metabolism included ester hydrolysis, methylation, ester hydrolysis combined with decarboxylation, hydroxylation, ester hydrolysis combined with indazole ring hydroxylation, etc.

while glucuronidation served as the main metabolic pathway of the phase II metabolism.

Additional information
Quantity

10 grams, 100 grams, 1000 grams, 1gram, 25 grams, 250 grams, 2grams, 5 grams, 50 grams, 500 grams

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