SEJIE RESEARCH CHEM SHOP | 6-MAPB,ADB-FUBINACA,METHYLONE
SEJIE RESEARCH CHEM SHOP
Login / Register

Sign inCreate an Account

Lost your password?
Wishlist
0 items / $0.00
Menu
SEJIE RESEARCH CHEM SHOP
0 items / $0.00
  • Home
  • About Us
  • Our Catalogue
  • Payment Options
  • Product Categories
    • Research Chemicals
    • Stimulants
    • Synthetic Cannabinoids
  • Delivery Info
  • Testimonials
  • Contact Us
JWH-018
Click to enlarge
HomeSynthetic Cannabinoids Buy JWH-018 Online
Previous product
Alprazolam powder
Buy Alprazolam powder Online $45.00 – $3,950.00
Back to products
Next product
JWH-019
Buy JWH-019 Online $30.00 – $1,880.00

Buy JWH-018 Online

$25.00 – $2,500.00

JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor:

Clear

Compare
Add to wishlist
SKU: N/A Category: Synthetic Cannabinoids Tags: Buy JWH-018 Online, JWH-018 For Sale, Order JWH-018 Online, Where to buy JWH-018 Online
Share
Facebook Twitter Pinterest linkedin Telegram
  • Description
  • Additional information
  • Shipping & Delivery
Description

JWH-018 (1-pentyl-3-(1-naphthoyl)indole) or AM-678 is an analgesic chemical from the naphthoylindole family

BUY JWH 018 (AM678)

JWH 018 (AM678

that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2.

It produces effects in animals similar to those of tetrahydrocannabinol (THC),

a cannabinoid naturally present in cannabis, leading to its use in synthetic cannabis products that in some countries are sold legally as “incense blends”.

As a full agonist at both the CB1 and CB2 cannabinoid receptors, this chemical compound is classified as an analgesic medication.

The analgesic effects of cannabinoid ligands, mediated by CB1 receptors are well established in treatment of neuropathic pain, as well as cancer pain and arthritis.

These compounds work by mimicking the body’s naturally-produced endocannabinoid hormones such as 2-AG and anandamide (AEA), which are biologically active and can exacerbate or inhibit nerve signaling.

As the cause is poorly understood in chronic pain states, more research and development must be done before the therapeutic potential of this class of biologic compounds can be realized

JWH 018  is an analytical reference material categorized as a synthetic cannabinoid. It has been found in Spice/K2-type herbal blends and may have neurotoxic properties. JWH 018 is regulated as a Schedule I compound in the United States.

Technical Information
Formal Name
1-naphthalenyl(1-pentyl-1H-indol-3-yl)-methanone
CAS Number
209414-07-3
Molecular Formula
C24H23NO
Formula Weight
341.5
Purity
≥98%
Formulation(Request formulation change)
A neat solid
Solubility
  • DMF: 10 mg/ml
  • DMSO: 10 mg/ml
  • Ethanol: 10 mg/ml
  • Methanol: 30 mg/ml
SMILES
CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
InChi Code
InChI=1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3
InChi Key
JDNLPKCAXICMBW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 73 months

Pharmacology
JWH-018 is a full agonist of both the CB1 and CB2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB1 and 2.94 ± 2.65 nM at CB2.

This product has an EC50 of 102 nM for human CB1 receptors, and 133 nM for human CB2 receptors.JWH-018 produces bradycardia and hypothermia in rats at doses of 0.3–3 mg/kg, suggesting potent cannabinoid-like activity.

Additional information
Quantity

10 grams, 100 grams, 1gram, 1kg, 20 grams, 2grams, 5 grams, 50 grams, 500 grams

Shipping & Delivery

Related products

4-fluoro
Compare
Close

Buy 4-fluoro Online

$27.00 – $1,490.00
4-Fluoro-4-methylaminorex or 4F-4-MAR (4F-MAR) is a new stimulant drug of the 2-amino-5-aryloxazoline class, developed as a replacement for 4-methylaminorex, aminorex. The effects of 4F-MAR are similar to methamphetamine, but have a longer lasting effect as shown in chemical studies in rodents. You can only buy 4F-MAR (4-Fluoro-4-methylaminorexR) online as a designer drug for chemical research.
Add to wishlist
Select options
Quick View
BUY SDB-006 POWDER
Compare
Close

Buy SDB-006 POWDER online

$26.00 – $2,100.00
BUY SDB-006 POWDER SDB-006 is a drug that acts as a potent agonist for the cannabinoid receptors, with an EC50
Add to wishlist
Select options
Quick View
Buy 5F-AKB48 POWDER online
Compare
Close

Buy 5F-AKB48 POWDER online

$26.00 – $2,800.00
Buy 5F-AKB48 -Sale Online Buy 5F-AKB48 -Sale Online, 5F-AKB48 (More so defined as 5F-APINACA). Well known as a synthetic class of  designer
Add to wishlist
Select options
Quick View
JWH-019
Compare
Close

Buy JWH-019 Online

$29.00 – $1,550.00
JWH 019 is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid (CB1) and the peripheral cannabinoid (CB2) receptors.
Add to wishlist
Select options
Quick View
Compare
Close

Buy BB-22 POWDER online

$27.00 – $1,950.00
BUY BB-22 POWDER (QUCHIC or 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a designer drug offered by online vendors as a cannabimimetic
Add to wishlist
Select options
Quick View
Buy UR-144 Powder online
Compare
Close

Buy UR-144 Powder online

$24.00 – $2,800.00
Buy UR-144 Powder (TMCP-018, KM-X1, MN-001, YX-17) is a drug invented by Abbott Laboratories, that acts as a selective full
Add to wishlist
Select options
Quick View
Compare
Close

Buy AM-2201 crystal online

$23.00 – $2,650.00
buy AM-2201 crystal AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for
Add to wishlist
Select options
Quick View
Compare
Close

Buy AB-CHMINACA Crystal online

$24.00 – $1,700.00
AB-CHMINACA is an indazole-based synthetic cannabinoid. It is a potent agonist of the CB₁ receptor and CB₂ receptor and fully
Add to wishlist
Select options
Quick View
Featured Products
  • U47700 Buy U47700 Online $38.00 – $2,310.00
  • Buy 5F-MN24 Powder online $45.00 – $3,600.00
  • Buy Dibutylone Crystal online $30.00 – $1,700.00
  • BK-EBDP Buy BK-EBDP Online $30.00 – $1,870.00
Best Selling Products
  • CP-47,497 Buy CP-47,497 Online $35.00 – $2,200.00
  • Buy UR-144 Powder online Buy UR-144 Powder online $24.00 – $2,800.00
  • MDMB-4en-PINACA Buy MDMB-4en-PINACA Online $28.00 – $3,000.00
  • FUB-144 Buy FUB-144 Online $25.00 – $1,000.00
Recent Products
  • eam2201 Buy eam2201 Online $35.00 – $580.00
  • ab-fubinaca Buy ab-fubinaca Online $30.00 – $2,002.00
  • ab-chminaca Buy ab-chminaca Online $34.00 – $775.00
  • Th-pvp crystal Buy Th-pvp crystal Online $36.00 – $2,500.00
Top Rated Products
  • JWH-051 Buy JWH-051 Online $28.00 – $1,350.00
  • JWH-122 Buy JWH-122 Online $30.00 – $2,800.00
  • SGT-151 Buy SGT-151 Online $35.00 – $5,500.00
  • U47700 Buy U47700 Online $38.00 – $2,310.00
SEJIE RESEARCH CHEM SHOP 2022 CREATED BY CREATED BY SEJIE RESEARCH CHEM SHOP
payments

Shopping cart

close
close
Start typing to see posts you are looking for.
  • Menu
  • Categories
Set your categories menu in Theme Settings -> Header -> Menu -> Mobile menu (categories)
  • Home
  • About Us
  • Our Catalogue
  • Payment Options
  • Product Categories
    • Research Chemicals
    • Stimulants
    • Synthetic Cannabinoids
  • Delivery Info
  • Testimonials
  • Contact Us
  • Wishlist
  • Login / Register
Scroll To Top