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MDMB-4en-PINACA
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HomeSynthetic Cannabinoids Buy MDMB-4en-PINACA Online
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SKU: N/A Category: Synthetic Cannabinoids Tags: Buy MDMB-4en-PINACA Online, MDMB-4en-PINACA For Sale, Order MDMB-4en-PINACA Online, Where to buy MDMB-4en-PINACA Online
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Description

MDMB-4en-PINACA is a new synthetic indazole cannabinoid. MDMB-4en-PINACA is analogous to 5F-MDMB-

PINACA and has a similar molecular structure. MDMB-4en-PINACA might display high affinity for peripheral CB1

and CB2 cannabinoid receptors. MDMB-4en-PINACA is marketed online as the designer drug cannabinoid.

A chemical researcher, called MDMB-4en-PINACA , is a designer drug with potential physiological and psychoactive effects.

The side-effects of MDMB-4en-PINACA are unknown.

Storage conditions of this chemical: in a cool and dry place. The stability of this chemical compound can last up to 2 years, under the right storage conditions.

Synonyms
Synonyms
  • MDMB-PENINACA
  • MDMB-PINACA N1-pentyl-4-en isomer
Technical Information
Formal Name
3-methyl-N-[[1-(4-penten-1-yl)-1H-indazol-3-yl]carbonyl]-L-valine, methyl ester
CAS Number
2504100-70-1
Molecular Formula
C20H27N3O3
Formula Weight
357.5
Purity
≥98%
Formulation(Request formulation change)
A neat solid
Solubility
  • DMF: 12 mg/ml
  • DMSO: 12 mg/ml
  • DMSO:PBS (pH 7.2)(1:8): 0.11 mg/ml
  • Ethanol: 10 mg/ml
SMILES
O=C(N[C@@H](C(C)(C)C)C(OC)=O)C1=NN(CCCC=C)C2=C1C=CC=C2
InChi Code
InChI=1S/C20H27N3O3/c1-6-7-10-13-23-15-12-9-8-11-14(15)16(22-23)18(24)21-17(19(25)26-5)20(2,3)4/h6,8-9,11-12,17H,1,7,10,13H2,2-5H3,(H,21,24)/t17-/m1/s1
InChi Key
LWOCBHBFWNGPGM-QGZVFWFLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 7 years

The next generation of synthetic cannabinoids: Detection, activity, and potential toxicity of pent-4en and but-3en analogues including MDMB-4en-PINACA

A new class of synthetic cannabinoids has emerged as new psychoactive substances (NPS). Similar in structure to JWH-022, these substances contain alkene modifications to the tail region of the synthetic cannabinoid core

structure, and nomenclature denotes these new analogues as pent-4en or but-3en species. Internationally, two analogues from this new series recently emerged: MDMB-4en-PINACA and MMB-4en-PICA. Previously, data

regarding activity and potential toxicity were not available. In vitro assessment of cannabinoid receptor 1 (CB1)

activation via the β-arrestin 2 recruitment was studied for three (3) pent-4en analogues, one  but-3en analogue, and one (1) principal metabolite. MDMB-4en-PINACA (2.47 nM, 239%), MDMB-4en-PICA (11.5 nM, 302%), and

MDMB-3en-BINACA (14.3 nM, 286%) were highly potent and efficacious (comparison: JWH-018

25.3 nM, 100%), while the potencies of MMB-4en-PICA and MDMB-4en-PINACA 3,3-dimethylbutanoic acid were

markedly lower. Modifications to core and tail structural features (i.e., indole vs. indazole) led to relatively small

differences in potency, while changes among the head region led to larger differences. Sample-mining and data-

mining conducted on toxicology samples led to the identification of MDMB-4en-PINACA in 25 forensic toxicology cases, i

Additional information
Weights

100grams, 10grams, 1gram, 1Kg, 250grams, 25grams, 2grams, 5 grams, 500grams, 50grams

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5F-MDMB-2201 also called 5-fluoro MDMB-PICA and N-[[1-(5-fluoropentyl)-1H-indol-3-yl]carbonyl]-3-methyl-L-valine, methyl ester, 5F-MDMB-2201 is specifically an Idazole-3-Carboaminide chemical, and as such has similar chemical
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