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NembutalJWH-019
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Buy Nembutal JWH-019 Online

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SKU: N/A Category: Synthetic Cannabinoids Tags: Buy NembutalJWH-019 Online, NembutalJWH-019 For Sale, Order NembutalJWH-019 Online, Where to buy NembutalJWH-019 Online
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Description

What is JWH-019 ?

JWH-019 is an analgesic chemical from the naphthoylindole family that acts as a cannabinoid agonist at both the CB1 and CB2 receptors.

JWH-019

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It is the N-hexyl homolog of the more common synthetic cannabinoid compound

JWH-018. Unlike the butyl homolog JWH-073, which is several times weaker than

JWH-018, the hexyl homolog is only slightly less potent, although extending the

chain one carbon longer to the heptyl homolog JWH-020 results in dramatic loss of activity.

These results show that the optimum side chain length for CB1 binding in the

naphthoylindole series is the five-carbon pentyl chain, shorter than in the

classical cannabinoids where a seven-carbon heptyl chain produces the most potent compounds.

This difference is thought to reflect a slightly different binding conformation adopted by the naphthoylindole

compounds as compared to the classical cannabinoids, and may be useful in characterizing the active site of the CB1 and CB2 receptors.

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(1-(5-hydroxypentyl)-1H-indol-3-yl)(4-methoxynaphthalen-1-yl)methanone
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